Buy 10ml Sterile Vials
ALK 20mm 10ml sterile empty vials with caps are perfect for a variety of applications. These sterile empty vials are certified depyrogenated, sealed and are type 1 borosilicate glass with butyl anf FluroTec coated stoppers. Sterilization process is performed in ALK's FDA inspected facility.
buy 10ml sterile vials
A multi-dose vial is a vial of liquid medication intended for parenteral administration (injection or infusion) that contains more than one dose of medication. Multi-dose vials are labeled as such by the manufacturer and typically contain an antimicrobial preservative to help prevent the growth of bacteria. The preservative has no effect on viruses and does not protect against contamination when healthcare personnel fail to follow safe injection practices.
Multi-dose vials should be dedicated to a single patient whenever possible. If multi-dose vials must be used for more than one patient, they should only be kept and accessed in a dedicated clean medication preparation area (e.g., nurses station), away from immediate patient treatment areas. This is to prevent inadvertent contamination of the vial through direct or indirect contact with potentially contaminated surfaces or equipment that could then lead to infections in subsequent patients. If a multi-dose vial enters an immediate patient treatment area, it should be dedicated for single-patient use only.
Medication vials should always be discarded whenever sterility is compromised or cannot be confirmed. In addition, the United States Pharmacopeia (USP) General Chapter 797 [16] recommends the following for multi-dose vials of sterile pharmaceuticals:
American Regent discontinued sterile water for injection in early-2021.
Fresenius Kabi had sterile water on shortage due to increased demand.
Hikma did not provide a reason for the shortage.
Medefil has sterile water for injection in syringes on shortage due to increased demand.
Pfizer has sterile water for injection in vials on shortage due to increased demand.
Fresenius Kabi has sterile water for injection 20 mL vials on back order and the company cannot estimate a release date. The 100 mL vials are on back order and the company estimates a release date of early-April 2023.
Hikma has sterile water for injection on allocation.
Pfizer has sterile water for injection 50 mL vials available in limited supply. The 100 mL vials are on back order and the company estimates a release date of June 2023.
Problem: Ongoing drug shortages in healthcare have become commonplace, with only the severity and urgency of the issue changing with the specific drugs in short supply. According to numerous inquiries to ISMP and frequent communications with Erin Fox, PharmD, BCPS, FASHP, a recognized expert in drug shortages at the University of Utah Health, current shortages of 0.9% sodium chloride for injection vials, prefilled saline flushes, sterile water for injection vials, and EPINEPHrine injection emergency syringes and autoinjectors, are all creating serious safety concerns and requiring even more effort from healthcare facilities to circumnavigate. (The University of Utah provides information for the American Society of Health-System Pharmacists [ASHP] Drug Shortages Resource Center.)
The most impactful shortage involves 0.9% sodium chloride in 10 mL, 20 mL, and 50 mL preservative-free, single-dose vials, prefilled flush syringes, and certain small volume (25 mL, 50 mL, 100 mL) bags. Shortages of the 0.9% sodium chloride vials have increased the demands for prefilled flush syringes, small volume bags, and vials of 23.4% sodium chloride, which have resulted in the current shortages of these products. Sodium chloride 0.9% is often needed to dilute or reconstitute certain medications. Also, nurses regularly use prefilled saline flush syringes, which are essential for vascular access device (VAD) maintenance and to reduce the risk of bloodstream infections.
Most sterile water for injection vials (i.e., 5 mL, 10 mL, 20 mL, 50 mL, 100 mL) are in short supply. These vials are primarily used to reconstitute medications available as lyophilized powders. While the prescribing information for some medications suggests that an alternative sterile liquid can be used for reconstitution, many specify that sterile water for injection must be used. The consequences of using a different sterile liquid to reconstitute medications may be unknown but could include poor dissolution of the powder, precipitation, or deactivation of the active pharmaceutical ingredient before administration.
It is an unsafe practice to prepare syringes used for flushing, dilution, or reconstitution for more than one patient from a common-source bottle or bag outside the pharmacy. In the pharmacy, the practice might be safe if primary engineering controls are used and strict sterile compounding regulations are followed. But outside of the pharmacy, there is a risk of contamination and disease transmission to a large group of patients, even if the solution is discarded after 24 hours. In addition, sterile water for irrigation is not labeled for use as an injection in patients. Sterile water for injection must pass a USP particulate-matter test that sterile water for irrigation does not have to pass, so they are not considered equivalent.
Under sterile conditions, reconstitute one (1) 25 mg vial of Indocyanine Green for Injection, USP using one (1) 10 mL Sterile Water for Injection, USP vial located in the ICG for Injection Set. Shake the ICG vial gently to dissolve. After reconstitution, a 25 mg vial of ICG contains 2.5 mg of dye per mL of solution, so a 1.0 mL injection contains a 2.5 mg dose of ICG.
Indocyanine green is a water soluble, tricarbocyanine dye with a peak spectral absorption at 800 nm. The chemical name for Indocyanine Green is 1 H-Benz[e]indolium, 2-[7-[1,3-dihydro-1,1-dimethyl-3-(4-sulfobutyl)-2H-benz[e] indol-2-ylidene]-1,3,5-heptatrienyl]-1,1-dimethyl-3-(4-sulfobutyl)-,hydroxide, inner salt, sodium salt. Indocyanine Green for Injection, USP has a pH of approximately 6.5 when reconstituted. Each vial of Indocyanine Green for Injection, USP contains 25 mg of indocyanine green as a sterile lyophilized powder.
Cath Loc HDS acts as a non-toxic anticoagulant lock solution for indwelling catheters for pre-clinical research. This is one of the most common formulations used as a reliable pre-clinical lock solution to maintain catheter patency in vascular catheters. This solution, used in both large and small animals, combines the high viscosity of 50% dextrose with the anticoagulant activity of heparin to promote and extended implanted catheter patency. The high osmolarity of dextrose prevents bacterial colonization and multiplication and the high viscosity of dextrose reduces washout from the catheter tip. The heparin in the solution also aids in prevention of clot formation. Since both dextrose and heparin are physiological constituents which occur naturally in the blood, any excess Cath-Lock HDS injected is quickly metabolized, when used properly. Available in 10ml sterile vials.
The compounding of a preservative-free high-concentration morphine sulfate injection from nonsterile morphine sulfate is described. High-concentration (50 mg/mL) morphine sulfate injection is compounded by dissolving Morphine Sulfate Powder, USP, in preservative-free sterile water for injection. The solution is pumped through 0.8- and 0.22-micrometer filters into 10-mL sterile vials and quarantined until assays for concentration, sterility, and bacterial endotoxins have been performed. The solution is placed in active inventory and dispensed to nursing units as needed. Total compounding cost per 10-mL vial of morphine sulfate injection is about $9. The expiration date is six months from the date of compounding. This solution has been administered i.m., s.c., i.v., and epidurally to inpatients with advanced cancer and severe pain at an acute care hospital. An acute care hospital compounds batches of preservative-free high-concentration morphine sulfate injection from nonsterile morphine sulfate.
HUMULIN N (insulin isophane human) injectable suspension is an intermediate acting human insulin. It is a sterile, white and cloudy suspension that contains insulin isophane human suspension (NPH) for subcutaneous use. Each milliliter of HUMULIN N contains 100 units of insulin human, dibasic sodium phosphate (3.78 mg), glycerin (16 mg), metacresol (1.6 mg), phenol (0.65 mg), protamine sulfate (0.35 mg), zinc oxide content adjusted to provide zinc ion (approximately 0.025 mg for the vials or approximately 0.035 mg for the KwikPen), and Water for Injection. The pH is 7.0 to 7.5. Sodium hydroxide and/or hydrochloric acid may be added during manufacture to adjust the pH.
Each prefilled HUMULIN N KwikPen is for use by a single patient. HUMULIN N KwikPens must never be shared between patients, even if the needle is changed. Patients using HUMULIN N vials must never share needles or syringes with another person.
Advise patients that they must never share a HUMULIN N KwikPen with another person, even if the needle is changed. Advise patients using HUMULIN N vials not to share needles or syringes with another person. Sharing poses a risk for transmission of blood-borne pathogens [see Warnings and Precautions (5.1)].
These transport tubes are designed to store and transport biological materials safely. The transparent polypropylene vials allow unobstructed viewing, and the molded graduations and frosted writing area make it easy to measure and mark samples. The tubes are also shatter-proof and may be exposed to freezing temperatures. Leak-resistant colored polyethylene screw caps can be removed or sealed in a single turn. 041b061a72